Duke Health researchers announces breakthrough in breast cancer vaccine trial

DURHAM, N.C. (WTVD) — Duke Health researchers recently announced groundbreaking results from a clinical trial that began over two decades ago.

A small group of women with advanced breast cancer participated in a trial where they received a vaccine, and all are alive today, with robust, long-lasting immune cells that recognize their cancer.

ABC11 spoke with Lori Lober, a study participant. Initially, she was given a grim prognosis, with median survival rate of less than 2 to 3% for five years. However, the trial at Duke Health gave her new hope. She has remained disease-free for 24 years.

“I just turned 62 on Halloween a few weeks ago, and I feel like one of the most blessed people on the entire planet because I live my life to the fullest,” Lober said.

Dr. Zachary Hartman of Duke Health highlighted the potential of immunotherapy.

“The real promise of it is that you could eliminate cancer cells throughout the body,” he said. “You’re not just like suppressing them temporarily, but you could actually kind of teach your body to go after them.”

Researchers are optimistic about the future of this approach in advancing cancer treatment.