What we know on the 12th day of the US and Israel’s war with Iran
A wave of strikes on Iran hit the capital and northern areas overnight into Wednesday, while Tehran launched what it called its “most intense” operation of the war, targeting Israel, Persian Gulf nations and ships passing through the Strait of Hormuz.
Throughout the region, a humanitarian crisis is mounting. The United Nations is warning of toxic black rain, mass displacement and disrupted supply chains for life-saving goods. And the death toll continues to rise.
Here’s what you need to know on day 12.
What are the main headlines?
A fireball rises from the site of an Israeli airstrike that targeted an area in Beirut’s southern suburbs overnight. – Fadel Itani/AFP/Getty Images
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New supreme leader’s condition: Mojtaba Khamenei suffered a fractured foot and other minor injuries in the first wave of US-Israeli strikes, a source familiar with the situation told CNN, amid rumors about his condition. Khamenei has not been seen in public nor issued a written statement since being chosen as Iran’s new supreme leader.
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Attacks in Strait of Hormuz: Iran attacked two vessels in the Strait of Hormuz today, the country’s Islamic Revolutionary Guard Corps (IRGC) said. One of them, the Thai-flagged bulk carrier Mayuree Naree, was fired on after “disregarding warnings and insistently attempting to illegally pass through,” the IRGC said. Three crew members remain unaccounted for. The strait, which Iran has effectively shut, is a crucial artery for the global economy since about one-fifth of the world’s oil supply passes through it. Oil prices rose again after the attacks.
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Russia-Iran ties: Russia is giving Iran specific advice on drone tactics, helping Tehran to hit US and gulf nation targets in the Middle East, a Western intelligence official told CNN. Russian intelligence sharing with Iran had previously been reported as general assistance with targeting; specific tactical advice represents a new level of support.
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Israeli strikes: Israel struck the Iranian capital multiple times on Wednesday and targeted a residential area, according to the Iranian Red Crescent. Israel also said it struck targets in Beirut and issued another sweeping evacuation order for residents in the south of the Lebanese capital. Sources tell CNN that Israel is preparing for a potential “significant expansion” of attacks from Iran and the Lebanon-based Hezbollah.
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Iran ramps up: Iran’s military said it launched its “most intense and heaviest operation” since the start of the war overnight into Wednesday, according to state media. The attack targeted locations in Israel and US assets in the region. The military has also threatened to strike ports and docks across the region if the country’s own ports are attacked.
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Growing death toll: Iran has accused the US and Israel of deliberately targeting civilians, with strikes killing more than 1,300 since the conflict started, according to Iran’s UN ambassador. In Lebanon, Israel’s strikes have killed more than 10 children every day so far, according to the UN children’s agency. Dozens more have been killed elsewhere around the region, including by Iranian strikes. Seven US service members have been killed and 140 others wounded, the Pentagon said Tuesday.
What else is happening in the region?

Members of Iran’s women’s soccer team arrive at the Kuala Lumpur International Airport – Arif Kartono/AFP/Getty Images
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Mines in the strait: The US military said it destroyed Iranian navy ships — including 16 minelayers — near the Strait of Hormuz. Sources earlier told CNN that Tehran has begun laying mines in the waterway, the world’s most important energy chokepoint, through which about one-fifth of global crude oil travels. But US President Donald Trump said he does not believe that Iran has successfully laid any mines in the strait.
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Regional attacks: Arab states in the Persian Gulf have been intercepting new waves of Iranian drones and missiles early Wednesday local time. A suspected Iranian drone also hit a US diplomatic facility in Iraq on Tuesday near the Baghdad airport, two sources told CNN.
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Toxic black rain: The World Health Organization is warning that black rain — contaminated rainfall — resulting from pollution could pose health risks after strikes in Iran. After fuel depots were hit last week, including in Tehran, thick plumes of black smoke billowed into the air, mixing with precipitation in the air to create toxic rain.
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Iranian soccer: Seven members of the Iranian women’s soccer team were granted humanitarian visas in Australia after seeking asylum, though one member changed her mind afterward and said she wanted to return home. The rest of the team left Sydney late Tuesday. Meanwhile, Iran’s sports minister said the country’s national soccer team cannot participate at this summer’s FIFA World Cup due to Iran’s ongoing war with the United States, a tournament co-host, and Israel.
What’s happening in the US?
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US terms: The White House laid out demands for what an “unconditional surrender” by Iran could look like, saying it will be personally determined by Trump. This includes dismantling Iran’s ballistic missile arsenal that “protects” its nuclear ambitions, the White House said. It added that Trump does “not rule options out” in the war, including deploying US ground troops. He told reporters that while the US has hit Iran “harder” than any country has been hit, “we’re not finished yet.”
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School strike: The Pentagon will release its report on a strike on an Iranian girls’ school that killed at least 168 children, the White House said Tuesday. The US military was likely responsible, according to CNN and expert analysis of evidence. And footage has emerged that appears to show a US missile targeting the Islamic Revolutionary Guard Corps naval base adjacent to the school. But Trump said he was unaware of a New York Times report that an ongoing military investigation has found, at least preliminarily, that the US was responsible.
Issy Ronald and Hira Humayun contributed to this report.
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